Department of Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Electronic address: Ruddy.kathryn@mayo.edu. Department of Biostatistics, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Department of Dermatology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY, 10065, USA. Inova Hematology Oncology, 8501 Arlington Blvd., Suite 340, Fairfax, VA, 22031, USA. Marshfield Clinic - Weston Center, 3501 Cranberry Blvd., Weston, WI, 54476, USA. Cancer and Hematology Centers of Western Michigan, 145 Michigan St. NE, #3100, Grand Rapids, MI, 49503, USA. Carle Cancer Center, 509 W. University Ave., Urbana, IL, 61801, USA. Department of Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.